It could happen but I doubt it will. New Oreleans has a very tough match up this week against the Patriots and after that there Schedule is not that easy having to versus Dallas, Atlanta, and Carolina. Im not saying it cant happen but I doubt it.
As for the Colts, they very well might end up undeafted. There only notiable games coming up I would have to say are Houston @ Home and Denver (But there on a losing streak lately), maybe the Titans could provide some trouble also, since there on a nice winning streak.