Arsenal I think will win the Premiership by about 6 points with Chelsea getting second. Then I think there will be about a 10 point gap and Liverpool will come in third with Manchester United a close fourth. I doubt Arsenal will keep their unbeaten run until the end of the season as there are too many tough games for them to play in the Premiership and they'll be more intersted in the Champions League.
I still don't think Arsenal will win the Champions League. They seem to lack something in that competition where on paper they are as good as anyone. Thierry Henry seems to go on the missing list whenever he plays for France National side or for Arsenal in the Champions League yet looks awesome in the Premiership week in week out, and without Henry firing on all cylinders Arsenal go from being a great side to a very good side. I myself would like either Arsenal or Chelsea to win the Champions League as they are both London teams.
There's no way Manchester United are ending the season first or second, they're just not good enough. They'll be lucky to reach the last eight in the Champions League.
I don't think any Americans will post as there is not much interest in their own Soccer Leagues in the US let alone the English Premiership.