score system and efficiency

I read somewhere that if you put your towers in an efficient way,
that you are able to kill the alines sooner than later you will get higher points, is this true?

Example:
1)Buy 3 towers, put them in a way that they kill alines as soon
as soon as they enter the stage.

2)Buy 3 towers, put them in the worst way i can and the alines
almost escape with the cores, but i do manage to kill them.

Will i get the same scores for the two scenarios?

Another question is about the Boost Towers.
If Boost Towers gives extra upgrades,
when would it be wrong not to use a Boost Tower?
I mean assuming i have the money for a Booster which pretty much will be always because they are cheap, why should I build a tower without building a Booster first?