Well, first, you should try to always find and get all of the time and point bonuses. When you get a point bonus, always try to go to places that normally have a lot of people in them. Also, try to conserve ammo for when you need it. For example, when you fight 1-3 enemies, use the pistol. When you're fighting the harder enemies, or multiple normal ones, use the riot shotgun. And, when need be, use a grenade or two. Like if you are facing a level boss, and there are multiple enemies around, use a couple grenades. The thing is, theres no real secret to winning these things. You just need a lot of time, and skill.
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